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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

It is unknown whether this difference in riboflavin status with age can be explained only by variations in dietary riboflavin intake

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Food may bypass parts of the intestine where important nutrients are normally absorbed

intermedia CA3-1 cells for industrial-scale nicotinic acid production ( FIGURE 5 Various matrices have been used for nitrilase immobilization using methods such as cross-linking and covalent bonding