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Description

In addition, during vaso-occlusive episodes, SCD patients show distinct metabolite profiles from those at steady-state 7,8,9,10

Site rotation and reconstitution/storage review are standard clinical guidance

Effects on fertility were long-lasting, indicating long-term protection of the ovarian reserve

After baseline collection, the participants breathed from a Douglas bag previously filled with pure oxygen for 4 min to remove nitrogen from the airways

Therefore, in order to contextualize the complexity of the metabolic network and the impact of Gclc on it, we analyzed our transcriptomic data using Compass, a flux balance analysis-based approach that allows the characterization and interpretation of metabolic diversity at the single cell level 70,71