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A total of 112 patients (10 studies) received cyclophosphamide, with an ORR of 49% (95% CI, 35-64), which was higher when cyclophosphamide was combined with corticosteroids (48%) and used in second-line treatment (58%) than in monotherapy (31%), and in first-line treatment (44%)

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139 The measurement of short-chain fatty acids (SCFAs) in saliva, produced by causal bacteria, may be an indicator of the inflammation degree closely related to the onset and progression of periodontal disease