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Description

The skin around the injection site is cleaned and sterilized, and a local anesthetic is applied to numb the area, minimizing discomfort

The Kraus 2014 study reported that adipocyte-specific NNMT knockdown in mice increased adipocyte energy expenditure through a mechanism interpreted as elevated methyl-donor availability for polyamine biosynthesis and for histone methylation that modulates adipocyte gene-expression programs [2]