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The satellite-cell hypothesis The central hypothesis around MGF is that its transient early expression after muscle injury serves to activate quiescent satellite cells the resident muscle stem cells pushing them into proliferation while delaying their terminal differentiation, thereby expanding the pool of myogenic precursors available for repair before the later, IGF-1Ea-driven phase completes the regeneration

The clinical relevance of the correlation between Nrf2 and MT gene polymorphisms and various illnesses, notably cardiovascular diseases, is highly significant

[DOI] [PubMed] [Google Scholar] 18.Larsson K.-H

Pesticides produce oxidative stress in the cell, which in turn generates several ROS free radicals [50]

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Santos SF, De Oliveira HL, Yamada ES, Neves BC, Pereira A