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Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria: identification, purification, characterization, and induction by peroxisome proliferators

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Because metabolite-receptor interactions are often highly stereospecific 53,54 , we developed a synthesis employing Sharpless chiral resolution and subsequent chirality transfer via Claisen rearrangement to access the two enantiomers of bemeth#1, (3 R) -bemeth#1 and (3 S) -bemeth#1 (Fig