glutathion radical scavenger Glutathione recycling and its importance in detoxification providing potent protection for your cells Mathematical model for glutathione dynamics

A mice model for PCOS has been developed (ob/ob mice that are also leptin deficient), where mice are: - obese - hyperglycemic - hyperinsulinemic - insulin-resistant - exhibiting increased TNF-a and IL-6 levels, which promotes the state of chronic low-grade inflammation

Diabetes 59:28462853 Kracht MJ, van Lummel M, Nikolic T, Joosten AM, Laban S, van der Slik AR, van Veelen PA, Carlotti F, de Koning EJ, Hoeben RC, Zaldumbide A, Roep BO (2017) Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

Furthermore, DNA damage caused by UV rays can be repaired by nucleotide repair and base excision mechanisms, apoptosis and cell cycle checkpoint system activation (31)

Salisbury BH, Terrell JM

Cellular benefits including telomere maintenance occur at the molecular level and may not produce immediate subjective effects

doi: 10.1016/j.critrevonc.2020.102988