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Berk M, Dean OM, Cotton SM, Jeavons S, Tanious M, Kohlmann K, et al

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Cross-linking changes compound these problems

This difference explains why stem cell and peptide therapy are increasingly considered a combined strategy

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According to a 2021 review on the subject, polyamines can be "used as an effective treatment" that promotes:4 Antioxidant capacity Cancer prevention Heart health Improved cognitive function The same 2021 review states that exogenous sources those from outside of the body provide the "maximum quantity" of polyamines, so food- and supplement-derived spermidine is essential to obtain the health benefits described above.4 How do spermidine supplements work