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GHK-Cu/Pionin-loaded in situ electrospun PVB/PVP smart dressing promotes wound healing via anti-oxidant, anti-inflammatory, antimicrobial, and tissue regenerative effects

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TB-500 distributes systemically regardless of injection location due to its longer half-life and different distribution characteristics

Typical weekly range: 0.64.5 mg once weekly (gradual titration over 46 weeks)

Microarray and RNA-sequencing studies have mapped its regulatory effect across approximately 4,000 human genes, including upregulation of VEGF, BDNF, and BMP-2 growth factors central to vascular, neural, and bone remodeling respectively