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Mice were genotyped by PCR using tail biopsies harvested between P10 and P14

In mammalian cells, APE1 also has a unique REDOX function, directing the activity of different transcription factors, thereby affecting gene expression and protein production [22]

The name is a mouthful, we know, but it describes what these spots are

Glutathione stops tyrosinase from making melanin, which is what makes skin darker