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Experimental Eye Research , 65 (3), 365378

Maybe youd heard of telomeres

Lead Time Accession Number Assay Time Sample Volume Storage Expiration Shipping Condition Research Area Quality Assurance Quality Guarantee Restrictions Quality Systems Technical Documents Selected Citations Featuring Biomatik's Products & Services Nature Communications , 10(1): 3667

Treatment induces p53-pS15 nuclear exclusion, triggering the apoptotic cascade specifically in senescent fibroblasts while sparing healthy cells

if the outer annulus fibrosus subsequently ruptures, the nucleus pulposus completely extrudes (non-contained herniation), potentially protruding into the spinal canal or lateral recess, compressing the cauda equina and nerve roots, causing pain or motor dysfunction (Figure 1)