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World Health Organ

While no single direct mechanism has been definitively established, fatigue likely results from multiple factors including substantial caloric restriction, gastrointestinal side effects, dehydration, and metabolic adaptation during weight loss

Vitamin B-Complex 100 Injection Prescribing information

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However, due to rare but serious adverse effects (e.g., thrombocytopenia, cardiac arrhythmias, hypersensitivity reactions), many guidelines recommend against routine use

Most patients describe the sensation as a mild vibrating or prickling feeling