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Pharmacological treatments can help alleviate fatigue and PEM, but their use is often accompanied by drawbacks such as insomnia, nausea, and the risk of dependence

5.6.1 Evidence of different mechanisms of action of Orthosiphon stamineus Benth

2023 Aug 1;15(16)

M., Corrado, A., Di Domenicantonio, A

The aforementioned results suggest that metformin could effectively inhibit erastin-induced ferroptosis to improve the survival of NSCs, and inhibition of AMPK phosphorylation with compound C counteracted the ferroptosis inhibitory effect of metformin

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