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Biochemical assessment includes blood tests for nutrient levels such as vitamins D, B12, folate, minerals like iron and zinc, and EFAs

Dysfunction of glutamatergic neurotransmission is a core feature of stress-related disorders, including MDD [27,28,29]

Conclusions A high index of suspicion for hyperammonaemia is mandatory in paediatric patients of any age with suggestive clinical symptoms, given that almost all survivors have developmental disabilities that correlate with the number, severity and duration of hyperammonaemic episodes

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Finally, I explain how foundational biology particularly sleep and cortisol rhythms shapes our capacity to navigate the grieving process