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A clinical trial shows improvement in skin collagen, hydration, elasticity, wrinkles, scalp, and hair condition following 12-week oral intake of a supplement containing hydrolysed collagen

However, challenges remain in the clinical translation of this cell therapy

10.1186/s12958-019-0520-9 68

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Additionally, the stimulated release of mitochondrial cytochrome c (cyt c) into the cytoplasm induces apoptotic cell death [25,26]

Interestingly, transplant survival rates were significantly higher in the QA model (20.1%) compared to the transgenic models with survival rates of approximately 17.89% in N171-82Q and only 9.61% in R6/2 mice