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While delivery systems based on viral or non-viral vectors have shown acceptable efficiency with an overall satisfactory safety profile, the applications of siRNA therapeutics remain challenging and should not be underestimated

In a systematic review, IBS patients were three times as likely as healthy subjects to have either anxiety or depression [17]

Are there cardiovascular effects, positive or negative, that only manifest over extended periods

12.5%, p 14kPa)

Statistical analysis All experiments were performed independently at least three times and the data were shown as mean and S.E.M

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