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The cases of hereditary occurrence of CRC constitute only about 5% [28]

Following the initial weight loss, a second stage more definitive procedure was performed, but researchers found that most patients achieved significant weight loss within 12 months after surgery

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Thus, considering also the natural inhibition of endocytosis in the BBB barrier, it is possible that early in infection, only a few meningococci can cross the barrier through the transcellular route