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Clinically, IDO1 inhibitors, evaluated in colorectal, pancreatic, and bladder cancers, demonstrate the potential to restore ferroptosis sensitivity and mitigate radiotherapy-induced immunosuppression in GBM

Here's what gets us excited: if a relatively small dose of oral glutathione (remember, only 20% gets absorbed) showed these benefits, imagine what IV delivery of therapeutic doses might accomplish

People taking medications, managing chronic conditions, or undergoing medical treatment should speak with a healthcare provider before adding NAC

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Targeted therapy resistance Resistance to targeted therapy can be intrinsic and acquired