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* Sweating * Headache * Dizziness **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Acne **Not Known (frequency cannot be estimated from the available data):** * Nerve damage (neuropathy) with prolonged use

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These data suggest that a specific subset of ATF4-dependent ISR-induced genes are likewise regulated by growth factor signaling through mTORC1 and are enriched for specific processes including aminoacyl tRNA synthesis, amino acid synthesis and uptake, and one-carbon metabolism

Iron plays an indispensable role in this process through Fenton chemistry, where iron catalyzes the production of reactive oxygen species (ROS) [140, 141]

Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, et al