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When doing a similar comparison with the 140 genes induced by superoxide/H 2 O 2 detected in the same study [124], 70 % (98 genes) were also induced by allyl-ITC at one of the three time points

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Success factors : Established eating habits Regular exercise routine Metabolic adaptation complete Sustainable calorie intake Reality : Many people stay on low maintenance dose long-term (2.5-5mg weekly)

MPP + treatment significantly reduces TIGAR expression in HT22 cells, downregulates NADPH, GPX4, and GSH levels, upregulates GSSG levels and the GSSG/GSH ratio, decreases adenosine triphosphate (ATP) production, and promotes neuronal ferroptosis, iron-dependent lipid peroxidation, and mitochondrial dysfunction, thereby exacerbating neuronal cytotoxicity