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Nature 438 , 10171021 (2005)

Chronic kidney disease (CKD) is characterized by reduced RBC production and introduces crucial changes in the structure and function of those cells

Targeting the TGF-/Smad3 signaling pathway significantly attenuates renal fibrosis (Yasuda et al., 2021)

The largest and fastest-growing markets are in the Asia-Pacific region, where skin bleaching agents are ubiquitous in drug stores, supermarkets, beauty stores, etc

However, studies to evaluate the regenerative potential of AT-MSCs-derived EVs in other tissues suggest that they may not fully replicate the regenerative efficacy of living AT-MSCs (147, 148)