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Moreover, concentrations of circulating endotoxin and the number of bacteria in the intestinal lymph nodes and the lymphatic circulation also correlate with disease severity [80]

One of these proteins is superoxide dismutase (SOD), which acts as the primary scavenger of host oxidative superoxide anion

In the latest EULAR and ACR guidelines for RA management, bDMARD tapering is considered a feasible practice in patients with sustained remission [21, 141]

10.3389/FNAGI.2022.998292/PDF [DOI] [PMC free article] [PubMed] [Google Scholar] Yin J, Jin X, Shan Z et al (2017) Relationship of sleep duration with all-cause mortality and cardiovascular events: a systematic review and dose-response meta-analysis of prospective cohort studies