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Established human cell lines as models to study anti-leukemic eects of avonoids

The structural components of folates can be categorized as follows: i) A heterocyclic pterin structure in oxidized or reduced form, consisting of a pyrimidine ring, a pyrazine ring and a methyl-group at carbon 6 that serves as a bridge for acid linkage

Cleanses toxins from the liver, supporting overall body detoxification

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Data availability Data is provided within the manuscript

This hypothesis is further strengthened by the fact that a mck1 strain (without CYS4 overexpression) shows slight methionine auxotrophy, which is rescued by the expression of wild-type MCK1 but not by a KD form of MCK1 (p.K68R, Figure 2D)