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Nearly 30 systematic reviews and meta-analyses have been published regarding ALAs beneficial effects in managing diabetes and its complications (Table 4)

doi: 10.3389/fnut.2023.1294057 37

10.1021/tx400431k Chem

Collectively, these studies highlight that pharmacological activation of Nrf2 can reduce ferroptosis and improve neurological deficits in preclinical models of ICH