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10.1186/1471-2105-16-s13-s4 37 HuangJ.CampianJ

(Engl.) 136 , 20142016 (2023)

Here's what we've learned: the interaction isn't pharmaceutical

Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

Even though taurine has low membrane permeability, it passes through the cells via the sodium/chloride dependent taurine transporter (TauT), which is committed to the transport of taurine from the extracellular to the intracellular compartments (7)