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Such disruptions can begin early, for example, when neonates in intensive care units are exposed to inappropriate light cycles, continue through infancy and adolescence with irregular exposure to screens and erratic eating patterns, persist into adulthood where jetlag and shift work are common, and extend into older age with increased sedentarism and psychosocial isolation

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T Kaneta 2020 PET and SPECT imaging of the brain: a review on the current status of nuclear medicine in Japan Jpn J Radiol 38 4 343 357 Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF (2011) Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Deionized or distilled water