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24 July 2026

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Maintain a healthy lifestyle: Engaging in regular exercise, reducing stress, and avoiding smoking and excessive alcohol consumption can all help support optimal B12 levels and enhance the effectiveness of B12 injections

In relapsed or refractory myeloma (R/R MM) patients, the CD38 expression levels are relatively high in NK cells, regulatory B cells (Bregs), Tregs and myeloid-derived suppressor cells (MDSCs) compared with CD8 + and CD4 + T cells, indicating that CD38 is involved in providing the immunosuppressive environment for tumor growth [19]

Although liver biopsy precisely detects the histological changes in the liver, we did not use this method in our research because of ethical issues