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The aspects include axonal injury, excitotoxicity, mitochondrial dysfunction, oxidative stress due to reactive oxygen species, neuroinflammation, axonal degeneration, growth inhibition, apoptotic cell death, and dysfunctional autophagy

However, its always recommended to perform a patch test before using any new skincare product to ensure compatibility and to consult with a dermatologist if you have any specific skin concerns or sensitivities

Potor et al., 2013)

Shores, J

Liquid chromatography/electrospray ionisation-mass spectrometry method for the quantification of sphingosine and sphinganine in cell cultures exposed to fumonisins

In summary, EGCG-induced hepatotoxicity involves the inhibition of major antioxidant enzymes, with the Nrf2 salvage pathway playing a crucial role in mitigating toxicity