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These combined effects are particularly intriguing for orthopedics because many musculoskeletal injuries (Achilles tendon ruptures, rotator cuff tears, chronic tendinopathies) occur in precisely those areas where blood flow is limited and healing is frustratingly slow

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[DOI] [PubMed] [Google Scholar] 29.Tkalcevi VI, Cuzi S, Brajsa K, Mildner B, Bokuli A, Situm K, Perovi D, Glojnari I, Parnham MJ

Beyond 8 weeks, diminishing returns set in and risk of tolerance increases

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Bacteria release proteases that chew up the peptide chain