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In any of these cases, the safest course is to discard the vial and start fresh

Zhang Y, Hu T, Hua C, Gu J, Zhang L, Hao S, et al

In vitro analysis showed that LSC-Exo was able to prevent the entry of SARS-CoV-2 pseudovirus into the ACE2 receptor-expressing A549 cells, similar to free rhACE2, whereas HEK-Exo showed little neutralization capacity against SARS-CoV-2 pseudovirus