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However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g

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Highly effective and safe oral antiretroviral therapies already exist, at a cost of less than US$50 a year, and the injectables price will need to be competitive against this

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The 40S-LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity