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Prediction of antiviral defense systems Bacterial defense systems against viral infections, such as CRISPRCas and abortive infection systems, were identified using a suite of bioinformatics tools: DefenseFinder 44 , PADLOC v2.0.0 45 , and CRISPRCasFinder 4.2.20 46

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The wound area was photographed immediately after wounding (0 hours), and again at 12 hours postscratch using brightfield exposure at 10 magnification on a Nikon eclipse 80i epifluorescence microscope