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doi: 10.3389/fimmu.2020.01783 81 WinterEMKooijmanSAppelman-DijkstraNMMeijerOCRensenPCSchilperoortM

Consequently, the release of cytochrome c results in the activation of the caspase cascade, including caspase 9 and caspase 3, and further amplifies the apoptotic signal 38