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Description

The expression of enzyme at tumor site are able to activate a simultaneously administered prodrug

Use Case

In PRKDC -deficient tumors, there were significantly greater messenger RNA (mRNA) expression of NK-related genes KLRC1 and NCR1 which encode NKG2A and NK cell p46 related protein (NKp46), respectively [132]

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Epigallocatechin-3-gallate: a phytochemical as a promising drug candidate for the treatment of Parkinsons disease

Through these immunosuppressive secretions, CAFs dampen the cytolytic activity of T cells and NK cells, allowing the tumor to grow relatively unchecked by the immune system