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Further exclusion criteria included studies lacking detailed methodologies, those without bioassays to reveal neuroprotective mechanisms, and those involving participants with severe metabolic conditions or serious medical conditions such as death during treatment (Fig

Think about how much systemic growth occurs during puberty, and then think about how the IGF-1 level required to yield that growth is only around the same amount of IGF-1 that the very low end of Acromegaly patients produce year round

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