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10.1016/j.bmcl.2009.07.068 Bioorg

When the immune system interacts with myelin proteins, it may relate to symptoms such as tingling, weakness, or balance changes

Treatment of mental health in patients with chronic liver disease

Reuben A, Zhang J, Chiou SH, Gittelman R, Li J, Lee WC, Quek K, Fujimoto J, Wang C, Behrens C, Kheradmand F, Chen R, Chow CW, Bernatchez C, Jalali A, Xin H, Wu CJ, Eerovic A, Parra E, Yusko E, Emerson R, Benzeno S, Vignali M, Wu X, Ye Y, Little L, Gumbs C, Mao X, Song X, Tippen S, Thornton R, Cascone T, Snyder A, Wargo J, Herbst R, Swisher SG , Kadara H, Moran C, Kalhor N, Zhang J, Scheet P, Vaporciyan AA, Sepesi B, Gibbons D, Robbins H, Hwu P, Heymach J, Sharma P, Allison J, Baladandayuthapani V, Lee J, Davis M, Wistuba I, Futreal PA, Zhang J

Researchers suggest that elevated gut pH, gut dysbiosis (i.e., a higher Firmicutes : Bacteroidetes ratio), obesity, or malabsorption might increase fecal SCFA, such as butyrate, which could have potential neurotoxic effects [25, 45, 46]

We have summarized the physiological and pathological mechanisms related to ferroptosis in MASLD (Figure 1) and summarized relevant research evidence