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Dietary patterns that limit animal products, age-related changes in digestion, certain medications, and increased metabolic demand can affect vitamin B12 needs

however, many other proteins remain poorly studied or unidentified, leaving significant gaps in our understanding of their specific roles in oxidative stress tolerance and pathogenesis [3]

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However, inhibitors of autophagy, necroptosis and apoptosis only partially improved survival substantially, suggesting that ferroptosis is essential for DOX-induced cardiomyopathy and mortality in mice [91]