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Protective immunity elicited by recombinant bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine

These include the thioredoxins and glutaredoxins, but we are also characterizing alternative pathways for disulfide bond reduction

The antiviral signaling pathways primarily include the IFN signaling pathway, the retinoic acid inducible gene I (RIG-I) signaling pathway, the cyclic GMPAMP synthase-stimulator of IFN genes (cGAS-STING) signaling pathway, and the TLR signaling pathway, among others

Transcriptomic analysis and pathway validation To further elucidate the mechanism of EGCG-Zn, we performed transcriptome sequencing on rectal tissues from control (Control), irradiated (RT), and EGCG-Zn-treated mice

H.NaralaS.ChunK

doi: 10.1038/nature10189