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Mitochondria in focus: from function to therapeutic strategies in chronic lung diseases

An increasing body of evidence indicates that natural bioactive compounds may provide adjunctive therapeutic advantages with a reduced incidence of adverse effects in comparison to traditional antidepressants

The acidic pH (approximately 4.5) required for hydrolases to function is set by an ATP-coupled proton pump, the vacuolar H + -ATPase (v-ATPase), and ion channels