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Description

It depends on the form of vitamin C

Conflicts of interest The authors have no conflict of interest to declare Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request

Pharmacologic treatments used for the components of the metabolic syndrome appear to be insufficient to control cancer development in subjects with metabolic syndrome

Activation of TGFB/SMAD signaling pathway in HOXC8-imESCs In the TGFB signaling pathway, SMAD2 and SMAD3 are activated via phosphorylation by TGFB receptors and translocated into the nucleus to regulate gene expression 29,30