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Brain 2022, 145: 27692784

By partially suppressing signal transduction and activators of transcription 1 (STAT1), hyperglycemia upregulates the expression of proinflammatory target genes, including CCL5 , CXCL10 , and ICAM1

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What areas of the body are treated with these technologies

doi:10.1016/j.jnutbio.2019.05.003 215

For example, ubiquitination of H2A can recruit methyltransferases such as polycomb repressive complex 1 and 2 (PRC1 and 2), ultimately resulting in methylation of H3K9 and H3K27 for transcriptional repression