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These targeted delivery systems bind to selective receptors with the help of appropriate nanocarriers (NCs) and technology [16]

However, the lack of standard protocols for the source, preparation, and application of stem cells has led to doubts about the authenticity and reproducibility of treatment outcomes

Dwivedi AK, Singh V, Anwar K, Pareek A, Jain M

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Metabolite mapping revealed limited biotransformation: the major species in plasma remained intact parent peptide, with minor degradation products formed by endopeptidases rather than DPP-4, corroborating the in vitro stability data [44]

The NLRP3 inflammasome complex, which is composed of the immune receptor NLRP3 protein, ASC, and caspase-1, plays a key role in the classical pathway [122]