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Figure 7 LA Supplementation Prevented FA-Induced xCT Reduction by Inhibiting p53 Activation P53 served as a major factor of cellular ferroptosis that respond to various injuries, and we further examined whether LA can protect from ferroptosis that was associated with p53 activation in tubular epithelial cells

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Results have been confirmed in three independent experiments

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Eur Heart J 2006;27:2170-6