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45,46 Increasingly, more studies have shown that G6PD activity is increased in several types of cancers, including bladder, breast, prostate, gastric cancers compared with normal tissues, and the high expression of G6PD predicts poor clinical outcome in various cancer patients and plays critical roles in tumorigenesis and chemoresistance

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doi: 10.1053/j.gastro.2013.11.049 53 EissingLSchererTTdterKKnippschildUGreveJWBuurmanWAet al

In addition to the signal pathways, downstream effector proteins and their activities in oxidant neutralization are discussed

The SakA (Hog1) and TscB (Sln1) two-component proteins in oxidant adaptation in Aspergillus fumigatus

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