melanotic macule increased melanocytes macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Pigmented lesions of the oral

Pigmented lesions of the oral cavity: An Update PMC Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review PMC Pathology Outlines Melanotic macule Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Smoker's Melanosis Benign oral mucosal pigmentation seen in smokers Due to increased melanin production, not melanocyte number Clinical Diffuse brown macules patches Usually flat, irregular Most common

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