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To control mineralization and cellular delivery, extracellular phosphate levels and total body phosphate content are tightly regulated by a number of hormones, including parathyroid hormone, 1,25-dihydroxy-vitamin D, and fibroblast growth factor-23 ( FGF23 ), and serum phosphate feeds back to regulate these factors in an endocrine fashion (Civitelli and Ziambaras, FGF23 , while low phosphate stimulates the synthesis of 1,25-dihydroxy-vitamin D

5.2.2 F2 generation effects (grandchildren) Remarkably, reproductive dysfunction persists in the F2 generation despite the absence of direct EED exposure

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Folic acid and supplementation with vitamins B6 and B12 also play key roles in converting homocysteine into methionine

It is a water-soluble vitamin that cats, like humans, need to obtain from external sources such as their diet or supplements