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Synapse Pro (25mg capsule, 30-count): A higher-dose formulation for patients who have demonstrated good tolerance on the 5mg protocol for at least 4 to 6 weeks and want to pursue a more aggressive cognitive enhancement timeline, or for patients whose provider determines a higher starting dose is clinically appropriate based on their specific presentation

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Inflammation grading was carried out independently by 3 researchers according to established protocols (77) and to the following scale: 0= No inflammation, 1= small pockets of cellular infiltrations, 2= small pockets of infiltrations less than 3 cells deep surrounding more than one airway or blood vessel, 3= infiltrations more than 3 cells deep found surrounding more than one but less than 50% of the total airways, 4=most airways surrounded by significant immune cell infiltrations, 5= the majority of airways are surrounded by significant immune cell infiltrations which also are seen present in alveolar beds