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Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

Aptamers are commonly conjugated with potent chemical drugs or biological medicines via cleavable linkers, which can be broken down to release the payloads upon exposure to environmental conditions such as low acidic pH, high redox, or high enzymatic activity

TSA markedly enhances NO production in human vascular ECs, potentially through the activation of eNOS (71)

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Metabolic measurements were conducted as representative experiments

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