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10.1210/jc.2003-031682 72 SehatB.TofighA.LinY.TrocmeE.LiljedahlU.LagergrenJ.et al

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Interestingly, the IC 50 of the cyclopropyl-AMP ester (9 M) is essentially identical to that of the ethyl-AMP inhibitor, indicating that the pocket is able to accommodate an alkyl group of this size and conformation