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A metal-organic framework (MOF) Fenton nanoagent-enabled nanocatalytic cancer therapy in synergy with autophagy inhibition

Notably, omega-6 and omega-9 fatty acid concentrations in Siamese Crocodile oil are about fourfold higher than those in fish oil (16)

[,,] The bile consists of ~95% water in which is dissolved a number of endogenous solid constituents consisting of bile salts, bilirubin phospholipid and cholesterol (these three main organic solutes form the mixed micelles in bile [] ), and also steroids, enzymes, AAs, porphyrins, vitamins, and heavy metals, as well as exogenous drugs, xenobiotics, and environmental toxins

The fact that autophagy-related factors (e.g., BECN1, mTOR, AMPK) can regulate specific regulatory ferroptosis networks also provides us with a new idea as to whether the occurrence of ferroptosis is somehow related to the signaling pathways that regulate autophagy

10.1002/jbt.22942 109 LiuJ.TangH.ChenF.LiC.XieY.KangR.et al (2024)